Fresh analysis suggests that people who stop using new slimming jabs like Mounjaro or Wegovy can put back on shed pounds far faster than those who halt conventional lifestyle programs.
Published data in a major health publication demonstrates that while obese people frequently drop substantial amounts of their body weight while on the medication, the mass returns at an average rate of 0.8 kg per month once they quit.
"People buying such medications need to be cognizant of the potential of quick rebound weight gain when the medication ends," cautioned researcher Dr. Susan Jebb.
That rate of recovery means a reversion to pre-treatment mass within about a year and a half.
Weighing Therapies
The research, which reviewed 37 of trials involving over 9,000 of patients, contrasted the effects of the injectable medications with older methods.
The team point out that people who shed pounds through diet and exercise usually have a slower creep back—around 100 grams monthly—after stopping.
Explaining the Quick Rebound
Experts believe the mode of action of the drugs is key to understanding the heightened rebound.
The injections mimic a natural hormone called glucagon-like peptide-1, which helps regulate appetite.
"Sustained high doses of GLP-1 concentrations far above than the body's typical production might result in the body to produce less of its endogenous hormone, and may also lessen responsiveness to its actions," noted Dr. Adam Collins, a nutrition researcher.
"Stopping of this hormone supplement leads to appetite is no longer kept in check, making binge eating much more probable."
A Lifelong Issue?
Medical guidelines recommend the injections for people with obesity-related health risks, accompanied by recommended diet and exercise modifications.
Many experts argue that, given the significant potential of weight regain, the treatment should be considered long-term.
This opinion is reinforced by pharmaceutical companies, who say that the results "highlight the persistent nature of excess weight," akin to managing diseases like hypertension.
User Accounts
Users who have stopped the medication explain a sudden resurgence of cravings.
"It was like a switch that goes on and you're instantly ravenous," said one woman.
This challenge is worsened if patients have not developed sustainable lifestyle or habit changes during therapy.
Widespread Interest
Recent estimates indicate that a significant number of adults in the UK have tried these injections in the last 12 months, with desire remaining high.
- Use is higher among females than males.
- The middle-aged age group shows the highest level of interest.
- Many access the drugs through private prescriptions rather than the NHS.
In conclusion, experts caution that while the jabs are effective tools for shedding pounds, they are not a standalone solution and lasting health benefits relies on combined behavioural support.
